Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274033 | 0.89 | ROCK2 (0.44) | ROCK2CD40CHRND | |
| SCHEMBL16274143 | 0.89 | ROCK2 (0.44) | ROCK2CD40CHRND | |
| SCHEMBL16156452 | 0.87 | SIRT2 (0.42) | SIRT2SIRT1ROCK2SIRT3SIRT5 | |
| SCHEMBL24728294 | 0.85 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL26273239 | 0.84 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5CHRND | |
| SCHEMBL24253175 | 0.83 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5HDAC1 | |
| SCHEMBL22214485 | 0.82 | SIRT2 (0.46) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20043710 | 0.81 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL18556695 | 0.81 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL22643511 | 0.81 | SIRT2 (0.49) | SIRT2SIRT1ROCK2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928902-B1 | CONJUGATE COMPOUNDS | VICTORIA LINK LTD (NZ) | 2019-07-17 | — | — | EP | disclosed |