Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24395102 | 0.86 | SIRT2 (0.35) | SIRT2SIRT1SIRT3CHRNA1CHRNG | |
| SCHEMBL21167802 | 0.84 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5CHRND | |
| SCHEMBL24728294 | 0.84 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL20197894 | 0.82 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL25774207 | 0.82 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL15699830 | 0.81 | SIRT5 (0.39) | SIRT2SIRT1SIRT3SIRT5CHRNA1 | |
| SCHEMBL23347043 | 0.81 | OPRK1 (0.38) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL20078727 | 0.81 | SIRT2 (0.34) | SIRT2SIRT1SIRT3SIRT5CHRNA1 | |
| SCHEMBL15699834 | 0.80 | MAP1LC3B (0.39) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL20043710 | 0.80 | SIRT2 (0.46) | SIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173026-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | SORRENTO THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |