SCHEMBL21168178

SCHEMBL21168178

FC(F)(F)C(c1ccc(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)cc1)(c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.38
MAPT P10636 6/20 0.38
MEN1 O00255 5/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 4/20 0.38
NTSR1 P30989 1/20 0.38
KDM4E B2RXH2 4/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.34
GLA P06280 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
TP53 P04637 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
POLB P06746 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168096 1.00 KMT2A (0.38) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168254 1.00 KMT2A (0.38) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168114 1.00 KMT2A (0.38) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168101 0.95 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168264 0.95 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168181 0.95 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168157 0.95 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168177 0.94 KDM4E (0.39) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL21168132 0.94 KDM4E (0.40) MAPTALDH1A1KDM4EATML3MBTL1
SCHEMBL21168057 0.94 KDM4E (0.40) MAPTALDH1A1KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-04-25 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-20210234113-A1 ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2021-07-29 US disclosed
US-20200259112-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-08-13 US disclosed
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2019-11-14 US disclosed
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT RPLP2, OPRD1, POLL KMT2A 2241/4885MAPT 2071/4885MEN1 1677/4885
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element RPLP2, OPRD1, POLL KMT2A 2241/4885MAPT 2071/4885MEN1 1677/4885
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 KMT2A 3082/4885MAPT 2421/4885MEN1 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.