SCHEMBL21168245

SCHEMBL21168245

FC(F)(F)C(c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(C(c4ccc(-n5c6ccccc6c6ccccc65)cc4)(C(F)(F)F)C(F)(F)F)cc3)n2)cc1)(c1ccc(-n2c3ccccc3c3ccccc32)cc1)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.45
KDM4E B2RXH2 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ABCG2 Q9UNQ0 5/20 0.38
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
HDAC4 P56524 1/20 0.36
DPP4 P27487 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
KIF11 P52732 1/20 0.34
PTPN1 P18031 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
GBA1 P04062 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168135 1.00 ATM (0.45) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168182 0.97 KDM4E (0.43) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168132 0.94 KDM4E (0.40) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168057 0.94 KDM4E (0.40) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168056 0.93 KDM4E (0.42) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168137 0.93 KDM4E (0.42) ATMKDM4EL3MBTL1ABCG2MGAM
SCHEMBL21168157 0.92 KMT2A (0.41) ATMKDM4EL3MBTL1ABCG2KMT2A
SCHEMBL21168181 0.92 KMT2A (0.41) ATMKDM4EL3MBTL1ABCG2KMT2A
SCHEMBL21168101 0.92 KMT2A (0.41) ATMKDM4EL3MBTL1ABCG2KMT2A
SCHEMBL21168264 0.92 KMT2A (0.41) ATMKDM4EL3MBTL1ABCG2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-04-25 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-20210234113-A1 ORGANIC LIGHT-EMITTING DEVICE KYULUX, INC. (JP) 2021-07-29 US disclosed
US-20200259112-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-08-13 US disclosed
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2019-11-14 US disclosed
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190348611-A1 LIGHT-EMITTING MATERIAL, COMPOUND, AND ORGANIC LIGHT-EMITTING ELEMENT RPLP2, OPRD1, POLL ATM 3694/4885KDM4E 3856/4885L3MBTL1 410/4885
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element RPLP2, OPRD1, POLL ATM 3694/4885KDM4E 3856/4885L3MBTL1 410/4885
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 ATM 1500/4885KDM4E 4193/4885L3MBTL1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.