SCHEMBL21168565

SCHEMBL21168565

c1ccc(-c2cncc(-c3cccc(-c4cccc5c4-c4ccccc4C54c5ccccc5-c5c(-c6cccc(-c7cncc(-c8ccccc8)n7)c6)cccc54)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.42
CYP11B2 P19099 2/20 0.41
CHEK1 O14757 1/20 0.40
CYP11B1 P15538 1/20 0.40
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
FYN P06241 1/20 0.34
SCN9A Q15858 1/20 0.34
PIM1 P11309 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
BRAF P15056 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168564 0.96 PDK2 (0.41) PDK2CYP11B2CHEK1CYP11B1FYN
SCHEMBL21168543 0.90 MEN1 (0.48) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL21168538 0.87 PDK2 (0.40) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL21168536 0.86 MEN1 (0.39) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL23873846 0.84 PDK2 (0.38) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL21168612 0.84 MEN1 (0.46) MEN1KMT2AADORA2AADORA1
SCHEMBL17031673 0.84 PDK2 (0.38) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL21168528 0.84 PDK2 (0.45) PDK2CYP11B2CYP11B1
SCHEMBL22073950 0.83 PDK2 (0.40) PDK2MEN1RAB9AKMT2AADORA2A
SCHEMBL21578583 0.83 PDK2 (0.40) PDK2MEN1RAB9AKMT2AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230126748-A1 POLYMER, A COMPOSITION, AND AN ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 US disclosed
US-20230126748-A1 POLYMER, A COMPOSITION, AND AN ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 US disclosed
US-11233200-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-01-25 US disclosed
US-20200212306-A1 QUANTUM DOT ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed
US-20190221746-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11233200-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound CRY1, CRY2, MCM4 PDK2 2534/4885CYP11B2 1099/4885CHEK1 500/4885
US-20190221746-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND CRY1, CRY2, MCM4 PDK2 2534/4885CYP11B2 1099/4885CHEK1 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.