SCHEMBL2116872

SCHEMBL2116872

CCCCCCCCCCCCCCCCCC(=O)OCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PAM P19021 2/20 1.00
▸ DGKA P23743 1/20 0.67
▸ GPR84 Q9NQS5 7/20 0.58
▸ PPARG P37231 7/20 0.58
▸ PPARD Q03181 7/20 0.58
▸ PPARA Q07869 7/20 0.58
▸ HDAC11 Q96DB2 5/20 0.58
▸ TSHR P16473 5/20 0.58
▸ PTPN1 P18031 3/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ TLR2 O60603 2/20 0.58
▸ TDP1 Q9NUW8 2/20 0.58
▸ FABP4 P15090 2/20 0.58
▸ SLC22A6 Q4U2R8 1/20 0.58
▸ SLC22A8 Q8TCC7 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ ESR1 P03372 1/20 0.58
▸ ALOX15 P16050 1/20 0.58
▸ PDE4A P27815 1/20 0.58
▸ KMT2A Q03164 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11345548 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL27957389 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL7773521 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL7775439 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL4725841 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL11354026 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL11047565 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL10555970 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL8671140 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD
SCHEMBL9602505 1.00 PAM (1.00) PAMDGKAGPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003794-B1 TESTOSTERONE ESTERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1981-01-28 — — EP claimed
CN-118234717-A Bicyclic heteroaromatic compounds and their use as pest control agents PI工业有限公司 2024-06-21 — — CN disclosed
CN-116917283-A Isoxazoline compounds and their use as pest control agents 皮埃企业有限公司 2023-10-20 — — CN disclosed
US-20230304002-A1 TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES BANK OF AMERICA, N.A. 2023-09-28 — — US disclosed
US-20230272382-A1 COMPLEMENT COMPONENT C3 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING COMPLEMENT COMPONENT C3-ASSOCIATED DISEASES BANK OF AMERICA, N.A. 2023-08-31 — — US disclosed
US-11161917-B2 Method for producing cellulose derivative, and cellulose derivative NEC CORPORATION (JP) 2021-11-02 — — US disclosed
EP-3222156-B1 FLAVOR IMPROVEMENT METHOD FOR YEAST CELLS AND FOOD QUALITY IMPROVING AGENT TABLEMARK CO LTD (JP) 2021-10-27 — — EP disclosed
US-11089806-B2 Flavor improvement method for yeast cells and food quality improving agent TABLEMARK CO., LTD. (JP) 2021-08-17 — — US disclosed
US-20190048099-A1 METHOD FOR PRODUCING CELLULOSE DERIVATIVE, AND CELLULOSE DERIVATIVE NEC CORPORATION (JP) 2019-02-14 — — US disclosed
EP-2597156-B1 METHOD FOR MANUFACTURING A FAT-SOLUBLE BIOACTIVE SUBSTANCE KANEKA CORP (JP) 2018-06-27 — — EP disclosed
US-4339389-A POLYETHERS, POLYESTERS, POLYEPOXIDES HENKEL CORPORATION (US) 1982-07-13 — — US disclosed
US-4307224-A POLYESTERS BASED ON BIS(HYDROXYMETHYL) OCTADECANOL HENKEL CORPORATION (US) 1981-12-22 — — US disclosed
US-4304945-A High molecular weight products HENKEL CORPORATION (US) 1981-12-08 — — US disclosed
US-4243818-A High molecular weight products HENKEL CORPORATION (US) 1981-01-06 — — US disclosed
US-4229562-A CURABLE ELASTOMER PRODUCES MOLDABLE MICROCELLULAR FOAM HENKEL CORPORATION (US) 1980-10-21 — — US disclosed
EP-0017503-A2 Gem-bis (hydroxymethyl) alcohols and mixtures thereof with diols, process for their preparation and a process for the preparation of polyurethanes therefrom HENKEL CORPORATION (a Delaware corp.) (US) 1980-10-15 — — EP disclosed
US-4216344-A High molecular weight polyol mixtures HENKEL CORPORATION (US) 1980-08-05 — — US disclosed
US-4216343-A High molecular weight polyhydric alcohols HENKEL CORPORATION (US) 1980-08-05 — — US disclosed
US-4066585-A THERMOPLASTIC BINDERS SCHERING AKTIENGESELLSCHAFT (DT) 1978-01-03 — — US disclosed
US-4059549-A POLYURETHANE, ENAMINE SCHERING AKTIENGESELLSCHAFT (DT) 1977-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230304002-A1 TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES TTR, MTPN, CRYAA PAM 4870/4885DGKA 3847/4885GPR84 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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