Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18997367 | 0.83 | MAPT (1.00) | MAPTALDH1A1HPGDPLA2G1BATG4B | |
| SCHEMBL14851898 | 0.70 | PI4KB (0.61) | MAPTALDH1A1HPGDACHEGAA | |
| SCHEMBL9548088 | 0.65 | MAPT (0.57) | MAPTALDH1A1HPGDACHEGAA | |
| SCHEMBL12105689 | 0.64 | PLTP (0.63) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19415457 | 0.64 | NPC1 (0.69) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL22678223 | 0.64 | GALR2 (0.45) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4840175 | 0.63 | MAPT (0.67) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL5909573 | 0.63 | CNR1 (0.64) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL1302331 | 0.63 | FBP1 (0.49) | MAPTALDH1A1HPGDGAAPTGDR2 | |
| SCHEMBL918248 | 0.62 | MAPT (1.00) | MAPTALDH1A1HPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870657-B2 | Compounds for the treatment of cancer and inflammatory disease | SHY Therapeutics LLC (US) | 2020-12-22 | — | — | US | disclosed |
| US-20190218229-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMTORY DISEASE | SHY Therapeutics LLC | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218229-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMTORY DISEASE | MAPK1, MAPK6, MAP3K1 | MAPT 2188/4885ALDH1A1 2861/4885HPGD 253/4885 |
| US-10870657-B2 | Compounds for the treatment of cancer and inflammatory disease | MAPK6, MAP3K6, MAPK4 | MAPT 2731/4885ALDH1A1 2765/4885HPGD 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.