Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18105881 | 0.86 | CYP4F2 (0.64) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL18105883 | 0.86 | CYP4F2 (0.64) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL6000185 | 0.84 | LOXL2 (0.70) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL5277923 | 0.83 | CYP4F2 (0.68) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL45113 | 0.83 | MRGPRX4 (0.57) | MRGPRX4ALDH1A1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL27450239 | 0.82 | MRGPRX4 (0.56) | MRGPRX4ALDH1A1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL18105808 | 0.82 | LOXL2 (0.52) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL18105809 | 0.82 | LOXL2 (0.52) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E | |
| SCHEMBL28277763 | 0.81 | MRGPRX4 (0.58) | MRGPRX4ALDH1A1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL28869399 | 0.81 | LOXL2 (0.62) | LOXL2CYP4F2CYP4A11MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274340-B1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA INC (US) | 2019-07-17 | — | — | EP | disclosed |