Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27565675 | 0.99 | HTR2A (0.61) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| SCHEMBL27585564 | 0.93 | HTR2A (0.60) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL27585384 | 0.90 | HTR2A (0.49) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL27565589 | 0.88 | HTR2A (0.53) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL27565603 | 0.88 | HTR2A (0.53) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL27565660 | 0.88 | HTR1A (0.48) | HTR2AHTR1ATMEM97ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27565601 | 0.88 | HTR1A (0.48) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL27565647 | 0.87 | KDM4E (0.58) | HTR2AHTR1ADRD2HTR2BKCNH2 | |
| SCHEMBL27565654 | 0.87 | HTR2A (0.59) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL28747789 | 0.85 | HTR2A (0.50) | HTR2AHTR1ATMEM97HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216793-A1 | COMPOSITIONS AND METHODS FOR TREATING NEGATIVE SYMPTOMS IN NON-SCHIZOPHRENIC PATIENTS | MINERVA NEUROSCIENCES, INC. | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216793-A1 | COMPOSITIONS AND METHODS FOR TREATING NEGATIVE SYMPTOMS IN NON-SCHIZOPHRENIC PATIENTS | GBA2, SLC6A3, COMT | HTR2A 163/4885HTR1A 172/4885TMEM97 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.