Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 6/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12287850 | 0.91 | MTOR (0.38) | IL1BPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL14990965 | 0.84 | PSEN1 (0.36) | IL1BMTORTNF | |
| SCHEMBL14990365 | 0.82 | GAA (0.41) | IL1B | |
| SCHEMBL21170312 | 0.80 | ABL1 (0.47) | ABL1 | |
| SCHEMBL12289987 | 0.80 | JAK2 (0.44) | ABL1CHEK2 | |
| SCHEMBL21170079 | 0.79 | QPCT (0.39) | IL1BTNF | |
| SCHEMBL2561842 | 0.79 | TNKS (0.43) | — | |
| SCHEMBL21170272 | 0.78 | IL1B (0.39) | IL1BTNF | |
| SCHEMBL21170124 | 0.77 | ABL1 (0.37) | IL1BABL1TNF | |
| SCHEMBL12286540 | 0.77 | TYMS (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3127541-B1 | CERTAIN AMINO-PYRIDAZINES, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | CYTOKINETICS INC (US) | 2019-07-17 | — | — | EP | disclosed |