Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329451 | 0.78 | CASP6 (0.82) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1143141 | 0.74 | MEN1 (0.76) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7937679 | 0.74 | MEN1 (0.68) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19329387 | 0.72 | CASP6 (0.59) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1039064 | 0.71 | MEN1 (0.71) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19329318 | 0.70 | CASP6 (0.68) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL26715282 | 0.69 | MEN1 (0.67) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL5282343 | 0.68 | CASP6 (0.54) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19329522 | 0.67 | CASP6 (0.61) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19329380 | 0.67 | CASP6 (0.61) | CASP6MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190218308-A1 | RESTORATION OF T CELL ACTIVITY VIA THE CD39/CD73 AXIS | INNATE PHARMA (FR) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218308-A1 | RESTORATION OF T CELL ACTIVITY VIA THE CD39/CD73 AXIS | ENTPD5, ENTPD1, ENTPD2 | CASP6 950/4885MEN1 2832/4885KMT2A 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.