Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.68 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329451 | 0.91 | CASP6 (0.82) | CASP6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19329634 | 0.82 | HDAC3 (0.53) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329690 | 0.80 | ALDH1A1 (0.48) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329488 | 0.79 | CASP6 (0.50) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329406 | 0.79 | ALDH1A1 (0.75) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329572 | 0.78 | MEN1 (0.51) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329447 | 0.78 | ALDH1A1 (0.53) | CASP6ACLYMEN1KMT2AMAPK1 | |
| SCHEMBL19329412 | 0.78 | CASP6 (0.48) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329860 | 0.77 | HTR6 (0.62) | CASP6MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL19329385 | 0.77 | ALDH1A1 (0.56) | CASP6MEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | claimed |
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |