Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17696414 | 0.83 | POLB (0.43) | OPRK1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL12038024 | 0.81 | OPRK1 (0.44) | OPRK1PKMHTTALDH1A1MAPT | |
| SCHEMBL19967034 | 0.81 | KDM4E (0.50) | OPRK1HTTLMNASMN1; SMN2HPGD | |
| SCHEMBL24969948 | 0.80 | HRH4 (0.51) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL12267527 | 0.79 | POLB (0.66) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL2544335 | 0.79 | CHRNB2 (0.54) | — | |
| SCHEMBL765394 | 0.79 | LRRK2 (0.44) | OPRK1KMT2AMEN1NPSR1 | |
| SCHEMBL3690660 | 0.78 | KMT2A (0.49) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL30903327 | 0.77 | CHRNB2 (0.53) | — | |
| SCHEMBL14853344 | 0.74 | KMT2A (0.44) | KMT2AMEN1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511332-A1 | NOVEL 2-ACYLAMINOTHIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2019-07-17 | — | — | EP | disclosed |