SCHEMBL21170437

SCHEMBL21170437

O=C(O)CCCCCCCCCCCCCCC(=O)NC(CCCCNC(=O)CO)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 4/20 0.53
FOLH1 Q04609 2/20 0.51
GLP1R P43220 8/20 0.50
EPHX2 P34913 3/20 0.49
GNPAT O15228 1/20 0.49
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27436076 0.87 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL14238761 0.87 NOD1 (0.52) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL12518531 0.87 NOD1 (0.52) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL23129208 0.87 NOD1 (0.52) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL21172243 0.87 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL23365799 0.87 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL20414814 0.87 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL21172899 0.87 NOD1 (0.55) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL21126875 0.87 NOD1 (0.52) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL21172279 0.87 GLP1R (0.48) NOD1FOLH1GLP1REPHX2FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 EP disclosed