SCHEMBL23129208

SCHEMBL23129208

O=C(O)CCCCCCCCCCCCCCC(=O)NC(CCCCNC(=O)CI)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 2/20 0.52
FOLH1 Q04609 7/20 0.50
GLP1R P43220 8/20 0.49
EPHX2 P34913 1/20 0.48
GNPAT O15228 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20414839 0.89 GLP1R (0.61) NOD1FOLH1GLP1R
SCHEMBL20528860 0.88 FOLH1 (0.49) NOD1FOLH1
SCHEMBL20528861 0.88 FOLH1 (0.49) NOD1FOLH1
SCHEMBL30905812 0.88 NOD1 (0.64) NOD1FOLH1GLP1REPHX2
SCHEMBL24179874 0.88 GLP1R (0.48) NOD1FOLH1GLP1R
SCHEMBL21170437 0.87 NOD1 (0.53) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL21172243 0.86 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL23365799 0.86 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL21126875 0.86 NOD1 (0.52) NOD1FOLH1GLP1REPHX2GNPAT
SCHEMBL21172899 0.86 NOD1 (0.55) NOD1FOLH1GLP1REPHX2GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11219690-B2 Method for thioether conjugation of proteins NOVO NORDISK HEALTHCARE AG (CH) 2022-01-11 US disclosed
EP-3079722-B1 METHOD FOR THIOETHER CONJUGATION OF PROTEINS NOVO NORDISK HEALTHCARE AG (CH) 2021-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11219690-B2 Method for thioether conjugation of proteins TST, P4HB, PDIA6 NOD1 2513/4885FOLH1 205/4885GLP1R 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.