Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115560 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1885037 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7307 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7306 | 0.72 | CYP3A4 (0.34) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5472 | 0.72 | KMT2A (0.36) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3617869 | 0.72 | RIPK1 (0.45) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL616123 | 0.69 | KMT2A (0.34) | ALDH1A1KDM4EMEN1KMT2ATHRB | |
| SCHEMBL2518702 | 0.69 | RIPK1 (0.40) | ALDH1A1KDM4EMEN1KMT2ARIPK1 | |
| SCHEMBL2117085 | 0.68 | PDE2A (0.36) | SMN1; SMN2EPRS1 | |
| SCHEMBL2518672 | 0.67 | MEN1 (0.38) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PDPK1, PIK3CA | ALDH1A1 1059/4885NPSR1 3597/4885CYP1A2 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.