Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16944695 | 0.86 | OPRK1 (1.00) | OPRK1OPRM1OPRD1 | |
| SCHEMBL16944752 | 0.84 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL16944741 | 0.84 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL21170992 | 0.81 | OPRK1 (0.86) | OPRK1 | |
| SCHEMBL18993305 | 0.81 | OPRK1 (1.00) | OPRK1OPRM1OPRD1 | |
| SCHEMBL16944947 | 0.81 | OPRK1 (1.00) | OPRK1OPRM1OPRD1 | |
| SCHEMBL16945045 | 0.78 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL21171737 | 0.78 | OPRK1 (0.76) | OPRK1 | |
| SCHEMBL16945088 | 0.77 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL16944608 | 0.76 | OPRK1 (1.00) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884978-B1 | NOVEL KAPPA OPIOID LIGANDS | SCRIPPS RESEARCH INST (US) | 2019-07-17 | — | — | EP | disclosed |