SCHEMBL21171990

SCHEMBL21171990

N=C(N)NCCCCc1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
ASAH1 Q13510 1/20 0.49
CYP1A2 P05177 1/20 0.49
MC4R P32245 5/20 0.48
MC5R P33032 4/20 0.48
MC3R P41968 3/20 0.48
MC1R Q01726 2/20 0.48
PLAU P00749 1/20 0.47
SIGMAR1 Q99720 3/20 0.46
HCAR2 Q8TDS4 1/20 0.43
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21171920 0.80 TRPV1 (0.56) SIGMAR1
SCHEMBL21172158 0.80 MC4R (0.46) HDAC1HDAC8MC4RMC5RMC3R
SCHEMBL21171779 0.79 KDM4E (0.43) HDAC1HDAC8ASAH1CYP1A2
SCHEMBL21171993 0.79 VNN1 (0.49) HDAC1HDAC8CYP1A2MC4RMC5R
SCHEMBL30496740 0.79 IDO1 (0.55) HDAC1HDAC8CYP1A2MC4RMC5R
SCHEMBL4019637 0.79 IDO1 (0.55) HDAC1HDAC8CYP1A2MC4RMC5R
SCHEMBL21171905 0.79 MC5R (0.62) HDAC1HDAC8MC4RMC5RMC3R
SCHEMBL30418669 0.78 SIGMAR1 (0.68) HDAC1HDAC8CYP1A2MC4RMC5R
Hydrochloric Acid SCHEMBL28129376 0.78 IDO1 (0.54) HDAC1HDAC8CYP1A2MC4RMC5R
SCHEMBL21171908 0.77 MEN1 (0.50) HDAC1HDAC8SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11353461-B2 Methods of enhancing MS detection of tagged glycans WATERS TECHNOLOGIES CORPORATION (US) 2022-06-07 US disclosed
US-20190219587-A1 METHODS OF ENHANCING MS DETECTION OF TAGGED GLYCANS WATERS TECHNOLOGIES CORPORATION 2019-07-18 US disclosed