SCHEMBL21172212

SCHEMBL21172212

CCC(=O)NCCCCC(NC(=O)CCC(NC=O)C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 6/20 0.50
▸ FOLH1 Q04609 1/20 0.47
▸ GLP1R P43220 8/20 0.47
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ EPHX2 P34913 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548901 0.91 MEN1 (0.53) NOD1FOLH1MEN1KMT2AEPHX2
SCHEMBL21172197 0.85 GLP1R (0.61) NOD1FOLH1GLP1R
SCHEMBL14217259 0.83 MEN1 (0.59) NOD1FOLH1GLP1RMEN1KMT2A
SCHEMBL16472580 0.83 NOD1 (0.50) NOD1FOLH1GLP1RMEN1KMT2A
SCHEMBL24282431 0.81 NOD1 (0.51) NOD1FOLH1GLP1REPHX2
SCHEMBL21172243 0.80 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL27436076 0.80 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL23365799 0.80 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL20414814 0.80 NOD1 (0.58) NOD1FOLH1GLP1REPHX2
SCHEMBL14118103 0.80 NOD1 (0.50) NOD1FOLH1GLP1RMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 — — EP disclosed
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