SCHEMBL14217259

SCHEMBL14217259

CCC(=O)NCCCCC(NC(=O)CC)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
FOLH1 Q04609 7/20 0.51
NOD1 Q9Y239 4/20 0.50
EPHX2 P34913 1/20 0.46
ALB P02768 2/20 0.46
GLP1R P43220 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002349 0.95 MEN1 (0.55) MEN1KMT2AFOLH1NOD1EPHX2
SCHEMBL9905595 0.95 MEN1 (0.55) MEN1KMT2AFOLH1NOD1EPHX2
SCHEMBL15871316 0.90 ALB (0.56) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL24418072 0.89 FOLH1 (0.48) MEN1KMT2AFOLH1NOD1EPHX2
SCHEMBL14217261 0.87 GLP1R (0.47) MEN1KMT2AFOLH1NOD1EPHX2
SCHEMBL21172243 0.87 NOD1 (0.58) FOLH1NOD1EPHX2GLP1R
SCHEMBL20414814 0.87 NOD1 (0.58) FOLH1NOD1EPHX2GLP1R
SCHEMBL14998098 0.87 GLP1R (0.47) MEN1KMT2AFOLH1NOD1EPHX2
SCHEMBL23365799 0.87 NOD1 (0.58) FOLH1NOD1EPHX2GLP1R
SCHEMBL27436076 0.87 NOD1 (0.58) FOLH1NOD1EPHX2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695226-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-07-04 US disclosed
US-9695226-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-07-04 US disclosed
US-8822498-B2 Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS, INC. (US) 2014-09-02 US disclosed
US-8779109-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTH CARE AG (CH) 2014-07-15 US disclosed
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTH CARE AG (CH) 2014-04-17 US disclosed
US-20120309944-A1 Growth Hormones With Prolonged In-Vivo Efficacy NOVO NORDISK HEALTH CARE AG (CH) 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309944-A1 Growth Hormones With Prolonged In-Vivo Efficacy GHRHR, SHBG, GHSR MEN1 335/4885KMT2A 3639/4885FOLH1 343/4885
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM MEN1 335/4885KMT2A 3466/4885FOLH1 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.