SCHEMBL21172287

SCHEMBL21172287

CCC(=O)NCCCCC(NC(=O)COCCOCCNC(=O)CCC(C)C(O)O)C(O)O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.44
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.33
▸ RECQL P46063 1/20 0.30
▸ CASP2 P42575 1/20 0.30
▸ EPOR P19235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21172401 0.90 GLP1R (0.47) GLP1RMEN1KMT2AALDH1A1RECQL
SCHEMBL21172359 0.89 GLP1R (0.49) GLP1RMEN1KMT2AALDH1A1RECQL
SCHEMBL22627089 0.77 GLP1R (0.56) GLP1R
SCHEMBL12518540 0.77 GLP1R (0.60) GLP1R
SCHEMBL12424086 0.76 GLP1R (0.62) GLP1R
SCHEMBL19786696 0.74 GLP1R (0.59) GLP1RMEN1KMT2A
SCHEMBL24198474 0.73 GLP1R (0.48) GLP1RMEN1KMT2ARECQL
SCHEMBL71906 0.73 MEN1 (0.45) GLP1RMEN1KMT2ARECQL
SCHEMBL14683533 0.73 GLP1R (0.48) GLP1RMEN1KMT2ARECQL
SCHEMBL17401159 0.73 GLP1R (0.64) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 — — EP disclosed
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