Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.62 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | CNR2 | P34972 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CDC25B | P30305 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709967 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL8665013 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL30295637 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL9288049 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL20100237 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL27721668 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL4407176 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL27729056 | 0.98 | ALDH1A1 (0.74) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL27477086 | 0.97 | ALDH1A1 (0.72) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL9681013 | 0.97 | ALDH1A1 (0.72) | TSHRMAPK1CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170159189-A1 | METHOD FOR PRODUCING 1,5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2017-06-08 | — | — | US | claimed |
| CN-104558085-B | Naphthoic acid Pentamethylene. many hydrogen phenanthrene ester B and extracting method thereof and medicinal usage | 吉林农业大学 | 2016-08-17 | — | — | CN | claimed |
| CN-104558085-A | Naphthoic acid cyclopentanoperhydrophenanthrene ester B and extraction method and pharmaceutical application thereof | UNIV JILIN AGRICULTURAL | 2015-04-29 | — | — | CN | claimed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | claimed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | claimed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | claimed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | claimed |
| US-20170159189-A1 | METHOD FOR PRODUCING 1,5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2017-06-08 | — | — | US | disclosed |
| CN-104558085-B | Naphthoic acid Pentamethylene. many hydrogen phenanthrene ester B and extracting method thereof and medicinal usage | 吉林农业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104558085-B | Naphthoic acid Pentamethylene. many hydrogen phenanthrene ester B and extracting method thereof and medicinal usage | 吉林农业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104558085-B | Naphthoic acid Pentamethylene. many hydrogen phenanthrene ester B and extracting method thereof and medicinal usage | 吉林农业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104558085-A | Naphthoic acid cyclopentanoperhydrophenanthrene ester B and extraction method and pharmaceutical application thereof | UNIV JILIN AGRICULTURAL | 2015-04-29 | — | — | CN | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | disclosed |
| EP-0432910-B1 | Process for producing highly pure 2, 6 naphthalene dicarboxylic acid | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5326848-A | Thermotropic liquid crystal polyester | KURARAY CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5068410-A | Hydrolysis of 2,6-dimethyl naphthalene dicarboxylate in an aqueous solution using an aromatic polycarboxylic acid or anhydride as a catalyst | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0432910-A2 | Process for producing highly pure 2, 6 naphthalene dicarboxylic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-06-19 | — | — | EP | disclosed |
| US-4931420-A | COLOR CHANGING LABELS, CHIPS FOR STORED FOODS, MEDICINES, BLOOD; RUPTURABLE CAPSULES CONTAINING DYE AND DEVELOPER | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0244219-A2 | Temperature history indicator and its manufacture | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | TSHR 534/4885MAPK1 1555/4885CYP3A4 796/4885 |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | TSHR 534/4885MAPK1 1555/4885CYP3A4 796/4885 |
| US-20170159189-A1 | METHOD FOR PRODUCING 1,5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | DAO, APEX1, DDAH1 | TSHR 3769/4885MAPK1 812/4885CYP3A4 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.