Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 5/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21172680 | 0.88 | ADRB1 (0.40) | SMN1; SMN2TNFNOD2NOD1RAB9A | |
| SCHEMBL21172933 | 0.88 | PRKDC (0.46) | TNFNOD2NOD1RAB9AALDH1A1 | |
| SCHEMBL21172728 | 0.88 | ADRB1 (0.40) | SMN1; SMN2TNFNOD2NOD1RAB9A | |
| SCHEMBL21172640 | 0.88 | PRKDC (0.46) | TNFNOD2NOD1RAB9AALDH1A1 | |
| SCHEMBL24347304 | 0.83 | MAPT (0.47) | SMN1; SMN2TNFNOD2NOD1ALDH1A1 | |
| SCHEMBL21172495 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2CYP2C19ALDH1A1LMNAMEN1 | |
| SCHEMBL21172877 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2TNFNOD2NOD1RAB9A | |
| SCHEMBL24348374 | 0.80 | HPGD (0.49) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL24347983 | 0.79 | MAPT (0.40) | SMN1; SMN2ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL24347656 | 0.77 | TNF (0.47) | S100BSMN1; SMN2TNFNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511323-A1 | 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS | GlaxoSmithKline Intellectual Property (No.2) Limited (GB) | 2019-07-17 | — | — | EP | disclosed |