SCHEMBL21173402

SCHEMBL21173402

Cc1cccc(N(c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
KCNK3 O14649 1/20 0.41
ACHE P22303 1/20 0.39
KMT2A Q03164 7/20 0.38
MEN1 O00255 6/20 0.38
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 4/20 0.35
NPC1 O15118 2/20 0.35
NSD2 O96028 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP2D6 P10635 1/20 0.35
LMNA P02545 1/20 0.34
TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21173409 0.96 TSHR (0.42) TSHRKCNK3ACHEKMT2AMEN1
SCHEMBL18052481 0.95 TSHR (0.41) TSHRKCNK3ACHEKMT2AMEN1
SCHEMBL22779258 0.90 TSHR (0.39) TSHRKCNK3ACHEKMT2AMEN1
SCHEMBL13304337 0.89 TSHR (0.36) TSHRKCNK3ACHEKMT2AMEN1
SCHEMBL14342110 0.89 CNR1 (0.43) TSHRACHEKMT2AMEN1CYP3A4
SCHEMBL13372114 0.88 RELA (0.40) TSHRKCNK3KMT2AMEN1CYP3A4
SCHEMBL13358383 0.88 RELA (0.40) TSHRKCNK3KMT2AMEN1CYP3A4
SCHEMBL13358366 0.88 RELA (0.40) TSHRKCNK3KMT2AMEN1CYP3A4
SCHEMBL6758227 0.87 ALDH1A1 (0.39) TSHRACHEKMT2AMEN1CYP3A4
SCHEMBL13511242 0.87 TSHR (0.37) TSHRKCNK3ACHEKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3909958-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2021-11-17 EP disclosed
US-20190221375-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed