Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.43 |
| ▸ | CDK2 | P24941 | 5/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302280 | 0.82 | LRRK2 (0.50) | LRRK2 | |
| SCHEMBL14556210 | 0.78 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL21723720 | 0.77 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL7449816 | 0.74 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL28925019 | 0.74 | LRRK2 (0.50) | TTKLRRK2 | |
| SCHEMBL20537316 | 0.73 | ULK1 (0.50) | LRRK2 | |
| SCHEMBL25301733 | 0.73 | LRRK2 (0.44) | CCNA2CDK2LRRK2 | |
| SCHEMBL15507708 | 0.73 | TTK (1.00) | TTKCCNA2CDK2 | |
| SCHEMBL17024307 | 0.73 | TTK (0.65) | TTKCCNA2CDK2 | |
| SCHEMBL30623764 | 0.73 | TTK (1.00) | TTKCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293183-B1 | INHIBITOR COMPOUNDS | CANCER RESEARCH TECH LTD (GB) | 2019-07-24 | — | — | EP | disclosed |