Fluoride

Fluoride

SCHEMBL21173953

F.O=C(O)c1cc(C(=O)O)ncn1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 17/20 0.57
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
ASPH Q12797 2/20 0.48
KDM8 Q8N371 2/20 0.48
KDM6B O15054 1/20 0.48
TET3 O43151 1/20 0.48
KDM4A O75164 1/20 0.48
BBOX1 O75936 1/20 0.48
MAPT P10636 1/20 0.48
KDM5A P29375 1/20 0.48
KDM5C P41229 1/20 0.48
KDM4D Q6B0I6 1/20 0.48
TET2 Q6N021 1/20 0.48
ALKBH5 Q6P6C2 1/20 0.48
KDM7A Q6ZMT4 1/20 0.48
TET1 Q8NFU7 1/20 0.48
EGLN2 Q96KS0 1/20 0.48
FTO Q9C0B1 1/20 0.48
EGLN1 Q9GZT9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71141 0.97 KMO (0.59) KMOKDM4EALDH1A1ASPHKDM8
Hydrochloric Acid SCHEMBL3272369 0.94 KMO (0.57) KMOKDM4EALDH1A1ASPHKDM8
Hydrochloric Acid SCHEMBL3272233 0.94 KMO (0.57) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL17132794 0.85 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL15228305 0.85 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8
Pyrimidine SCHEMBL28981669 0.84 KMO (0.59) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL18167352 0.82 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL232129 0.82 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL14221342 0.82 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL19128953 0.80 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed