SCHEMBL71141

SCHEMBL71141

O=C(O)c1cc(C(=O)O)ncn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 16/20 0.59
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
ASPH Q12797 2/20 0.50
KDM8 Q8N371 2/20 0.50
KDM6B O15054 1/20 0.50
TET3 O43151 1/20 0.50
KDM4A O75164 1/20 0.50
BBOX1 O75936 1/20 0.50
MAPT P10636 1/20 0.50
KDM5A P29375 1/20 0.50
KDM5C P41229 1/20 0.50
KDM4D Q6B0I6 1/20 0.50
TET2 Q6N021 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
KDM7A Q6ZMT4 1/20 0.50
TET1 Q8NFU7 1/20 0.50
EGLN2 Q96KS0 1/20 0.50
FTO Q9C0B1 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3272233 0.97 KMO (0.57) KMOKDM4EALDH1A1ASPHKDM8
Hydrochloric Acid SCHEMBL3272369 0.97 KMO (0.57) KMOKDM4EALDH1A1ASPHKDM8
Fluoride SCHEMBL21173953 0.97 KMO (0.57) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL17132794 0.88 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL15228305 0.88 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8
Pyrimidine SCHEMBL28981669 0.86 KMO (0.59) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL18167352 0.85 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL232129 0.85 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL14221342 0.85 KMO (0.52) KMOKDM4EALDH1A1ASPHKDM8
SCHEMBL19128953 0.83 KMO (0.50) KMOKDM4EALDH1A1ASPHKDM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12017186-B2 Use of polyvinylpyrrolidone in the preparation of ana-ZMOF thin film membranes for separation processes KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) 2024-06-25 US claimed
CN-113699536-B Metal phosphide electrocatalyst based on MOF derivation, preparation method and application 安徽理工大学 2022-12-23 CN claimed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN claimed
US-20210394126-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA-ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES UNIV KING ABDULLAH SCI & TECH (SA) 2021-12-23 US claimed
CN-113699536-A Metal phosphide electrocatalyst based on MOF derivation, preparation method and application 安徽理工大学 2021-11-26 CN claimed
CN-113667136-A Ultrahigh-stability and low-cost metal-organic framework material for efficiently separating acetylene/carbon dioxide and preparation method thereof 浙江大学 2021-11-19 CN claimed
US-11142826-B2 Substitution-type electroless gold plating solution containing purine or pyrimidine-based compound having carbonyl oxygen and substitution-type electroless gold plating method using the same MK CHEM & TECH CO., LTD (KR) 2021-10-12 US claimed
CN-110923680-B Substituted electroless gold plating solution containing purine or pyrimidine compound having carbonyl oxygen and method using same MK化学科技有限公司 2021-09-24 CN claimed
CN-113332958-A Forming method of nitrogen-containing aluminum-based metal-organic framework material and air water absorption application thereof 浙江大学 2021-09-03 CN claimed
WO-2010062573-A1 SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF POLYMEDIX, INC. (US) 2010-06-03 WO claimed
US-20100105703-A1 Synthetic Mimetics Of Host Defense And Uses Thereof POLYMEDIX, INC. (US) 2010-04-29 US claimed
EP-1877412-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2008-01-16 EP claimed
US-20060287190-A1 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA 2006-12-21 US claimed
WO-2006116340-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2006-11-02 WO claimed
US-6936616-B2 Pyrimidine matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2005-08-30 US claimed
JP-2004518723-A 2004-06-24 JP claimed
EP-1368323-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS Warner-Lambert Company LLC (US) 2003-12-10 EP claimed
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors BARVIAN NICOLE CHANTEL (US) 2002-10-17 US claimed
WO-2002064571-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105703-A1 Synthetic Mimetics Of Host Defense And Uses Thereof TLR3, MYD88, TLR5 KMO 2296/4885KDM4E 2532/4885ALDH1A1 4441/4885
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors MMP13, MMP3, MMP11 KMO 1752/4885KDM4E 1484/4885ALDH1A1 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.