Dimethylamine

Dimethylamine

SCHEMBL21174852

C1=Cc2nc1c(-c1ccccc1)c1ccc([nH]1)c(-c1ccccc1)c1nc(c(-c3ccccc3)c3ccc([nH]3)c2-c2ccccc2)C=C1.CNC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.58
▸ TOP1 P11387 4/20 0.57
▸ STAT3 P40763 1/20 0.56
▸ STAT1 P42224 1/20 0.56
▸ CYCS P99999 4/20 0.55
▸ ABCG2 Q9UNQ0 1/20 0.50
▸ ENPP2 Q13822 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405434 0.93 TOP1 (0.64) TERTTOP1STAT3STAT1CYCS
SCHEMBL30136 0.93 TOP1 (0.64) TERTTOP1STAT3STAT1CYCS
SCHEMBL9640434 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL7987113 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL483081 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL991489 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL9418767 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL8014529 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL15085674 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS
SCHEMBL8014524 0.91 TOP1 (0.62) TERTTOP1STAT3STAT1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484890-B1 SELECTIVE PORPHYRIN-CATALYZED ELECTROCHEMICAL REDUCTION OF CO2 INTO CO, IN PARTICULAR IN WATER CENTRE NAT RECH SCIENT (FR) 2020-09-02 — — EP disclosed
US-20190224660-A1 SELECTIVE PORPHYRIN-CATALYZED ELECTROCHEMICAL REDUCTION OF CO2 INTO CO, IN PARTICULAR IN WATER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2019-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190224660-A1 SELECTIVE PORPHYRIN-CATALYZED ELECTROCHEMICAL REDUCTION OF CO2 INTO CO, IN PARTICULAR IN WATER CYC1, TFRC, PYCR1 TERT 747/4885TOP1 2973/4885STAT3 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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