Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 20/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21175497 | 0.91 | HDAC4 (0.79) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175487 | 0.87 | HDAC4 (0.63) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175486 | 0.86 | HDAC4 (0.61) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175488 | 0.85 | HDAC4 (0.77) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175484 | 0.83 | HDAC4 (0.67) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175480 | 0.83 | HDAC4 (0.63) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175513 | 0.82 | HDAC4 (0.77) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175475 | 0.82 | HDAC4 (0.65) | HDAC4HDAC6HDAC1 | |
| SCHEMBL21175504 | 0.82 | HDAC4 (0.79) | HDAC4HDAC6HDAC1 | |
| SCHEMBL20049298 | 0.82 | HDAC4 (0.62) | HDAC4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653146-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-19 | — | — | US | disclosed |
| US-20190223442-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190223442-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | NOX3, NOX1, MPO | HDAC4 1299/4885HDAC6 676/4885HDAC1 556/4885 |
| US-10653146-B2 | Microbiocidal oxadiazole derivatives | NOX3, NOX1, MPO | HDAC4 1299/4885HDAC6 676/4885HDAC1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.