Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 8/20 | 0.75 |
| ▸ | JAK2 | O60674 | 1/20 | 0.70 |
| ▸ | TYK2 | P29597 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | PNLIP | P16233 | 2/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15164875 | 0.91 | PNLIP (0.76) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL1203522 | 0.89 | SMO (0.80) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL5387595 | 0.87 | SMO (0.73) | SMOJAK2TYK2KMT2AMAPT | |
| Water SCHEMBL27602058 | 0.87 | SMO (0.77) | SMOJAK2TYK2KMT2AMAPT | |
| Chlorbenzuron SCHEMBL5177776 | 0.86 | GCGR (0.68) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL6300608 | 0.86 | SMO (0.71) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL14825061 | 0.86 | SMO (0.76) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL6819083 | 0.86 | SMO (0.71) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL95731 | 0.86 | SMO (0.71) | SMOJAK2TYK2KMT2AMAPT | |
| SCHEMBL19500975 | 0.86 | SMO (0.76) | SMOJAK2TYK2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| US-20120094038-A1 | USE OF HUMIDITY STABLE YELLOW FLUORESCENT PIGMENTS IN SECURITY APPLICATIONS | HONEYWELL INTERNATIONAL INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-6897316-B2 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-05-24 | — | — | US | disclosed |
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHUK | SMO 3556/4885JAK2 1793/4885TYK2 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.