SCHEMBL6300608

SCHEMBL6300608

O=C(Nc1ccc(F)cc1)c1ccccc1Cl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMO Q99835 6/20 0.71
LMNA P02545 2/20 0.70
JAK2 O60674 1/20 0.66
TYK2 P29597 1/20 0.66
RAB9A P51151 4/20 0.65
KMT2A Q03164 3/20 0.65
MAPT P10636 3/20 0.65
TDP1 Q9NUW8 3/20 0.65
MAPK1 P28482 3/20 0.65
MEN1 O00255 2/20 0.65
NPC1 O15118 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
GRM4 Q14833 1/20 0.65
RORC P51449 1/20 0.64
KDM4E B2RXH2 1/20 0.62
CYP1A2 P05177 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
HTT P42858 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11138747 0.87 TDP1 (0.67) SMOLMNAJAK2TYK2RAB9A
SCHEMBL2117583 0.86 SMO (0.75) SMOLMNAJAK2TYK2RAB9A
SCHEMBL1203522 0.85 SMO (0.80) SMOLMNAJAK2TYK2RAB9A
SCHEMBL28598714 0.85 CYP1A2 (0.62) SMOJAK2TYK2RAB9AKMT2A
SCHEMBL5387595 0.84 SMO (0.73) SMOLMNAJAK2TYK2RAB9A
Water SCHEMBL27602058 0.84 SMO (0.77) SMOLMNAJAK2TYK2RAB9A
SCHEMBL30729340 0.84 ALDH1A1 (0.65) LMNARAB9AKMT2AMAPTTDP1
SCHEMBL3403605 0.84 ALDH1A1 (0.65) LMNARAB9AKMT2AMAPTTDP1
SCHEMBL10703668 0.84 TDP1 (0.63) SMOLMNARAB9AKMT2AMAPT
SCHEMBL22819974 0.84 CYP1A2 (0.60) SMOLMNARAB9AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP disclosed
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-01 US disclosed
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-03-25 US disclosed
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-01-09 US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 US disclosed
US-6897316-B2 Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents CHINA MEDICAL UNIVERSITY (TW) 2005-05-24 US disclosed
US-20050032832-A1 Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents CHINA MEDICAL UNIVERSITY (TW) 2005-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885
US-20050032832-A1 Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHUK SMO 3556/4885LMNA 3189/4885JAK2 1793/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMO 509/4885LMNA 3364/4885JAK2 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.