Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898527 | 0.86 | MBOAT4 (0.76) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL28680586 | 0.85 | MBOAT4 (0.74) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL6477188 | 0.85 | MBOAT4 (0.74) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL28689586 | 0.85 | MBOAT4 (0.74) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL21176043 | 0.82 | MBOAT4 (1.00) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL21625866 | 0.80 | MBOAT4 (0.67) | MBOAT4CYP19A1SHBGSERPINA6CYP3A4 | |
| SCHEMBL11362671 | 0.79 | MBOAT4 (0.65) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL11362674 | 0.79 | MBOAT4 (0.65) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL21176005 | 0.77 | MBOAT4 (0.62) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 | |
| SCHEMBL219127 | 0.77 | MBOAT4 (0.62) | MBOAT4CDK5CDK5R1NR1I3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190224214-A1 | HUMAN GHRELIN O-ACYLTRANSFERASE INHIBITORS | SYRACUSE UNIVERSITY (US) | 2019-07-25 | — | — | US | disclosed |
| US-20190224214-A1 | HUMAN GHRELIN O-ACYLTRANSFERASE INHIBITORS | SYRACUSE UNIVERSITY (US) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190224214-A1 | HUMAN GHRELIN O-ACYLTRANSFERASE INHIBITORS | MBOAT4, LCAT, ACAT1 | MBOAT4 1/4885CDK5 1727/4885CDK5R1 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.