Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104971 | 0.84 | TDP1 (0.47) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL27733009 | 0.82 | TDP1 (0.45) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL28035472 | 0.80 | TDP1 (0.44) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL27953990 | 0.80 | MAPT (0.45) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL10624290 | 0.78 | MAPT (0.47) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL9407173 | 0.78 | TDP1 (0.42) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL27334438 | 0.78 | CA1 (0.48) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL27467233 | 0.78 | CA1 (0.44) | CA1CA2CA9HPGDALOX15 | |
| SCHEMBL111142 | 0.77 | TDP1 (0.45) | HPGDALOX15HSD17B10NSD2MEN1 | |
| SCHEMBL28297322 | 0.77 | CA1 (0.47) | CA1CA2CA9HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109679482-A | A kind of anti-sag Two-component Waterproof Polyurethane Coating and preparation method thereof | 徐州卧牛山新型防水材料有限公司 | 2019-04-26 | — | — | CN | claimed |
| US-20120094958-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2012-04-19 | — | — | US | claimed |
| EP-2250152-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | Novartis AG (CH) | 2010-11-17 | — | — | EP | claimed |
| WO-2009106586-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | claimed |
| CN-109912096-A | A kind of pretreated method of o-methyl formate benzene sulfonamide waste water sub-prime | 江苏南大华兴环保科技股份公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-207537376-U | Prepare the microreactor of o-methyl formate benzene sulfonamide | 苏州汶颢微流控技术股份有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-107522638-A | Prepare the microreactor and method of o-methyl formate benzene sulfonamide | 苏州汶颢微流控技术股份有限公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-107522638-A | Prepare the microreactor and method of o-methyl formate benzene sulfonamide | 苏州汶颢微流控技术股份有限公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-105085333-B | The preparation method of first sulfanilamide (SN) | 新乡市辉普化工科技有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-105085333-A | Preparation method of methyl o-sulphamoylbenzoate | XINXIANG HOPE CHEMICAL TECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | disclosed |
| US-20120094958-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2012-04-19 | — | — | US | disclosed |
| EP-2250152-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | Novartis AG (CH) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106586-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094958-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | FDPS, GGPS1, CTPS1 | CA1 4827/4885CA2 4371/4885CA9 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.