Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104971 | 0.82 | TDP1 (0.47) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL27733009 | 0.80 | TDP1 (0.45) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL2117606 | 0.80 | CA1 (0.52) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL27509871 | 0.79 | LMNA (0.55) | L3MBTL1MAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL27953990 | 0.78 | MAPT (0.45) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL9407173 | 0.77 | TDP1 (0.42) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL10624290 | 0.77 | MAPT (0.47) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| SCHEMBL27334438 | 0.77 | CA1 (0.48) | TDP1ATML3MBTL1HSD17B10ALOX15 | |
| Acetic Acid Phenyl Ester SCHEMBL1930995 | 0.77 | ELANE (0.60) | TDP1HSD17B10HPGDMAPTSMN1; SMN2 | |
| SCHEMBL111142 | 0.76 | TDP1 (0.45) | TDP1ATML3MBTL1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146361-A | Indenes-1-subunit sulfonyl benzoyl hydrazine derivant and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-105985265-A | Indene-1-subunit sulfonyl benzoyl hydrazine derivative as well as preparation method and application thereof | 四川大学 | 2016-10-05 | — | — | CN | disclosed |
| CN-105085333-A | Preparation method of methyl o-sulphamoylbenzoate | XINXIANG HOPE CHEMICAL TECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | disclosed |