Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 17/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHKB | Q9Y259 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820779 | 1.00 | CHKA (0.68) | CHKARAB9ACHKBALDH1A1 | |
| SCHEMBL21176115 | 1.00 | CHKA (0.68) | CHKARAB9ACHKBALDH1A1 | |
| SCHEMBL21190294 | 0.83 | CHKA (0.78) | CHKA | |
| SCHEMBL19820478 | 0.82 | CHKA (0.84) | CHKARAB9ACHKB | |
| SCHEMBL21190174 | 0.82 | CHKA (0.84) | CHKARAB9ACHKB | |
| SCHEMBL21176118 | 0.81 | CHKA (1.00) | CHKACHKB | |
| SCHEMBL19820528 | 0.81 | CHKA (1.00) | CHKACHKB | |
| SCHEMBL19820641 | 0.80 | CHKA (0.75) | CHKACHKB | |
| SCHEMBL19820636 | 0.80 | CHKA (0.75) | CHKACHKB | |
| SCHEMBL19813924 | 0.80 | CHKA (0.81) | CHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683292-B2 | Purine and 3-deazapurine analogues as choline kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2020-06-16 | — | — | US | claimed |
| US-20190225615-A1 | PURINE AND 3-DEAZAPURINE ANALOGUES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-07-25 | — | — | US | claimed |
| US-10683292-B2 | Purine and 3-deazapurine analogues as choline kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2020-06-16 | — | — | US | disclosed |
| US-20190225615-A1 | PURINE AND 3-DEAZAPURINE ANALOGUES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683292-B2 | Purine and 3-deazapurine analogues as choline kinase inhibitors | DCK, CHKA, ADK | CHKA 2/4885RAB9A 2111/4885CHKB 6/4885 |
| US-20190225615-A1 | PURINE AND 3-DEAZAPURINE ANALOGUES AS CHOLINE KINASE INHIBITORS | DCK, CHKA, ADK | CHKA 2/4885RAB9A 2111/4885CHKB 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.