SCHEMBL2117664

SCHEMBL2117664

N=C(N)NCCCC(N)C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.46
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
RRM1 P23921 1/20 0.40
NPY4R P50391 7/20 0.39
NPY1R P25929 5/20 0.39
NPY2R P49146 4/20 0.39
NPY5R Q15761 4/20 0.39
OTC P00480 1/20 0.39
PTGS1 P23219 1/20 0.38
GSTK1 Q9Y2Q3 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
PTGS2 P35354 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
DDAH1 O94760 1/20 0.37
NOS1 P29475 1/20 0.36
NOD1 Q9Y239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476574 1.00 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2117673 1.00 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL30259956 0.95 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL29630393 0.94 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL29350570 0.94 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL7996638 0.94 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL7996643 0.94 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
Aspartic Acid SCHEMBL28181767 0.92 DPP7 (0.40) DPP7GNAI3GNAO1GNAI1RRM1
Arginine SCHEMBL8437780 0.89 GSR (0.51) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL3505407 0.89 NPY4R (0.48) DPP7NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2010-03-04 US claimed
EP-1898943-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION Hadasit Medical Research Services & Development Ltd. (IL) 2008-03-19 EP claimed
WO-2006126188-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2006-11-30 WO claimed
US-20040116655-A1 Novel polypeptides and anti-hiv drugs containing the same BIOKINE THERAPEUTICS LTD. (IL) 2004-06-17 US claimed
EP-1323730-A1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME SEIKAGAKU CORPORATION (JP) 2003-07-02 EP claimed
EP-0677061-B1 POLYPEPTIDES AND ANTI-HIV AGENTS PREPARED THEREFROM SEIKAGAKU KOGYO CO LTD (JP) 1999-03-03 EP claimed
US-5776899-A Polypeptide and anti-HIV agent prepared therefrom SEIKAGAKU CORPORATION (JP) 1998-07-07 US claimed
CN-1038841-C Polypeptide and anti-hiv agent prepared therefrom SEIKAGAKU CO (JP) 1998-06-24 CN claimed
US-5627035-A Peptides that block human immunodeficiency virus and methods of use thereof SYNTELLO VACCINE DEVELOPMENT AB (SE) 1997-05-06 US claimed
CN-1116427-A Novel polypeptide and anti-HIV agent prepared from the same SEIKAGAKU KOGYO CO LTD (JP) 1996-02-07 CN claimed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP claimed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO claimed
EP-0545991-A1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE, Anders (SE) 1993-06-16 EP claimed
WO-1992003147-A1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF SYNTELLO VACCIN DEVELOPMENT KB (SE) 1992-03-05 WO claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
JP-2023849-A None JP disclosed
JP-7330572-A None JP disclosed
US-4217269-A FOR SPECTROPHOTOMETRIC MEASUREMENT OF PROTEOLYTIC ENZYMES ABBOTT LABORATORIES (US) 1980-08-12 US disclosed
US-4216142-A Chromogenic substrates for the proteolytic enzymes ABBOTT LABORATORIES (US) 1980-08-05 US disclosed
US-4029642-A CONDENSATION OF DES-B OCTAPEPTIDE WITH A PEPTIDE HOECHST AKTIENGESELLSCHAFT (DT) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization CXCR4, CXCL12, CXCR5 DPP7 1920/4885GNAI3 1817/4885GNAO1 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.