Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117664 | 0.89 | DPP7 (0.46) | GNAI3GNAO1GNAI1OTCDPP7 | |
| SCHEMBL29476574 | 0.89 | DPP7 (0.46) | GNAI3GNAO1GNAI1OTCDPP7 | |
| Arginine SCHEMBL301606 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL714211 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL8957537 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL15022773 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL3516723 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL11660904 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL4954180 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC | |
| Arginine SCHEMBL2143365 | 0.89 | GSR (0.65) | GSRGNAI3GNAO1GNAI1OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522004-B1 | USE OF COPPER(II) CONTAINING COMPOUNDS TO ACCELERATE WOUND HEALING | PROCYTE CORP (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5164367-A | Complexes with peptides | PROCYTE CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |