Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119235 | 0.89 | ABCB1 (0.71) | ABCB1ABCC1CYP11B1CYP11B2ACLY | |
| SCHEMBL2118244 | 0.85 | ABCB1 (0.51) | ABCB1ABCC1CYP11B1CYP11B2HTR6 | |
| SCHEMBL2120534 | 0.85 | ABCB1 (0.51) | ABCB1ABCC1CYP11B1CYP11B2HTR6 | |
| SCHEMBL2118531 | 0.85 | NAMPT (0.55) | ABCB1ABCC1HTR6ACLYPIK3CA | |
| SCHEMBL2120599 | 0.81 | KMT2A (0.51) | TSHRACLYKMT2AKITPOLB | |
| SCHEMBL12326414 | 0.78 | CYP2A6 (0.54) | ABCB1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2120627 | 0.75 | TRIM24 (0.59) | TSHRACLYKITPOLBALDH1A1 | |
| SCHEMBL19039682 | 0.73 | ABCB1 (0.47) | ABCB1ABCC1CYP11B1CYP11B2HTR6 | |
| SCHEMBL22230481 | 0.73 | TSHR (0.47) | TSHRPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL2119624 | 0.72 | SLC40A1 (0.47) | PIK3CAMTORKMT2APIK3CGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | ABCB1 2175/4885ABCC1 1204/4885TSHR 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.