Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 7/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177162 | 0.85 | SIGMAR1 (0.49) | CYP2A13CXCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL21177104 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTTHRH3SMN1; SMN2 | |
| SCHEMBL28454278 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EHTTHRH3SMN1; SMN2 | |
| SCHEMBL28449946 | 0.83 | SIGMAR1 (0.54) | ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL21177087 | 0.80 | SIGMAR1 (0.47) | CXCR4ALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL21177108 | 0.80 | MC4R (0.47) | ALDH1A1KDM4ENCF1HPGD | |
| SCHEMBL21177121 | 0.78 | KCNA3 (0.42) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL21177099 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL159991 | 0.72 | ALDH1A1 (0.53) | CYP2A13CXCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL27708992 | 0.71 | ALDH1A1 (0.51) | CYP2A13CXCR4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739070-B2 | C5A receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2023-08-29 | — | — | US | disclosed |
| EP-3740476-A1 | C5A RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-20200347029-A1 | C5A RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD. (CH) | 2020-11-05 | — | — | US | disclosed |
| CN-111615513-A | C5a receptor modulators | 爱杜西亚药品有限公司 | 2020-09-01 | — | — | CN | disclosed |
| WO-2019141803-A1 | C5A RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347029-A1 | C5A RECEPTOR MODULATORS | C5AR1, C3AR1, C5AR2 | CYP2A13 929/4885CXCR4 109/4885ALDH1A1 2987/4885 |
| US-11739070-B2 | C5A receptor modulators | C5AR1, C3AR1, C5AR2 | CYP2A13 929/4885CXCR4 109/4885ALDH1A1 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.