Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780593 | 0.87 | KLKB1 (0.37) | KLKB1PLAU | |
| SCHEMBL19779861 | 0.85 | CYP1A2 (0.38) | KLKB1RORCCYP3A4MAP4K1 | |
| SCHEMBL21179367 | 0.84 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL21179410 | 0.82 | HSP90AB1 (0.42) | KLKB1 | |
| SCHEMBL17442573 | 0.80 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL29302757 | 0.80 | KLKB1 (0.34) | KLKB1CYP3A4MAP4K1 | |
| SCHEMBL29940462 | 0.80 | KLKB1 (0.34) | KLKB1CYP3A4MAP4K1 | |
| SCHEMBL21179353 | 0.80 | KLKB1 (0.36) | KLKB1MAP4K1 | |
| SCHEMBL21177777 | 0.80 | KLKB1 (0.34) | KLKB1PLAUCYP3A4CYP2C19MAP4K1 | |
| SCHEMBL21177775 | 0.80 | KLKB1 (0.34) | KLKB1PLAUCYP3A4CYP2C19MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |