Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779861 | 0.85 | CYP1A2 (0.38) | KLKB1CACNA1HRAB9ACACNA1GCACNA1I | |
| SCHEMBL19780124 | 0.84 | GAA (0.39) | KLKB1CACNA1HMAPTALDH1A1 | |
| SCHEMBL19780593 | 0.84 | KLKB1 (0.37) | KLKB1THRB | |
| SCHEMBL19779862 | 0.83 | S1PR3 (0.38) | KLKB1CACNA1HALDH1A1 | |
| SCHEMBL21177281 | 0.80 | SIRT1 (0.38) | KLKB1MAP4K1 | |
| SCHEMBL21179410 | 0.80 | HSP90AB1 (0.42) | KLKB1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL21177775 | 0.79 | KLKB1 (0.34) | KLKB1CACNA1HALDH1A1MAP4K1 | |
| SCHEMBL21177777 | 0.79 | KLKB1 (0.34) | KLKB1CACNA1HALDH1A1MAP4K1 | |
| SCHEMBL21179367 | 0.79 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL21177153 | 0.77 | KLKB1 (0.43) | KLKB1MEN1KMT2ARAB9AMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |