Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | AKT1 | P31749 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CDC25A | P30304 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627911 | 1.00 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2119799 | 1.00 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2120325 | 1.00 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2120824 | 1.00 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2118513 | 1.00 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2120223 | 0.99 | LMNA (0.57) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2117742 | 0.96 | LMNA (0.54) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15389959 | 0.94 | TSHR (0.53) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15390256 | 0.94 | TSHR (0.53) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15390493 | 0.94 | TSHR (0.53) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318824-B2 | Hydrophilic polyolefin sintered body | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120095121-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2174975-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | Asahi Kasei Chemicals Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |