Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | AKT1 | P31749 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120223 | 0.97 | LMNA (0.57) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2117747 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2120325 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL3627911 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2119799 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2120824 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2118513 | 0.96 | LMNA (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15389624 | 0.94 | LMNA (0.47) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15390080 | 0.93 | AKT1 (0.49) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL15389834 | 0.91 | TSHR (0.50) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| EP-4713721-A1 | UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-03-10 | — | — | US | claimed |
| EP-3759528-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-02-03 | — | — | US | claimed |
| US-20250340028-A1 | CONTACT LENSES WITH SOFTER LENS SURFACES | ALCON INC (CH) | 2025-11-06 | — | — | US | claimed |
| US-20250303615-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2025-10-02 | — | — | US | claimed |
| US-11427685-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2022-08-30 | — | — | US | claimed |
| EP-3774310-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2022-07-06 | — | — | EP | claimed |
| EP-4017478-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | Alcon Inc. (CH) | 2022-06-29 | — | — | EP | claimed |
| EP-4017346-A1 | CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS | Alcon Inc. (CH) | 2022-06-29 | — | — | EP | claimed |
| EP-3989932-A1 | OPHTHALMIC COMPOSITIONS | Alcon Inc. (CH) | 2022-05-04 | — | — | EP | claimed |
| EP-3746820-B1 | CONTACT LENSES WITH A LUBRICIOUS COATING THEREON | ALCON INC (CH) | 2022-02-16 | — | — | EP | claimed |
| EP-2801401-B1 | OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR | LG CHEMICAL LTD (KR) | 2018-12-12 | — | — | EP | claimed |
| EP-2801401-A1 | OUTSTANDINGLY CONTAMINATION RESISTANT REVERSE OSMOSIS MEMBRANE AND PRODUCTION METHOD THEREFOR | LG Chem, Ltd. (KR) | 2014-11-12 | — | — | EP | claimed |
| US-8646617-B2 | Reverse osmosis membrane having good antifouling properties and method of manufacturing the same | LG CHEM, LTD. (KR) | 2014-02-11 | — | — | US | claimed |
| US-20130306550-A1 | REVERSE OSMOSIS MEMBRANE HAVING GOOD ANTIFOULING PROPERTIES AND METHOD OF MANUFACTURING THE SAME | LG CHEM, LTD. (KR) | 2013-11-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | INF2, CRYZ, CRYAA | LMNA 50/4885AKT1 2422/4885ESR1 2502/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | LMNA 2948/4885AKT1 4796/4885ESR1 2368/4885 |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | CRYAB, CRYZ, CRYAA | LMNA 219/4885AKT1 2739/4885ESR1 4484/4885 |
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | LMNA 1330/4885AKT1 2554/4885ESR1 3419/4885 |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | CRYZ, CRYAB, CRYAA | LMNA 1320/4885AKT1 3868/4885ESR1 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.