Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177806 | 0.85 | CYP3A4 (0.46) | CYP3A4TDP1ALDH1A1HTTMAPT | |
| SCHEMBL21186193 | 0.82 | NPC1 (0.58) | LMNAPDE10ACYP3A4TDP1ALDH1A1 | |
| SCHEMBL11109859 | 0.77 | RAB9A (0.68) | LMNACYP3A4TDP1ALDH1A1HTT | |
| SCHEMBL21186234 | 0.76 | RAB9A (0.47) | LMNACYP3A4TDP1ALDH1A1HTT | |
| SCHEMBL21186237 | 0.76 | ALDH1A1 (0.39) | LMNAPDE10ACYP3A4TDP1ALDH1A1 | |
| SCHEMBL10971640 | 0.74 | CYP3A4 (0.54) | LMNACYP3A4TDP1ALDH1A1HTT | |
| SCHEMBL21186395 | 0.74 | MAPT (0.38) | LMNAPDE10ACYP3A4TDP1ALDH1A1 | |
| SCHEMBL21186387 | 0.73 | CYP3A4 (0.48) | LMNAPDE10ACYP3A4TDP1ALDH1A1 | |
| SCHEMBL11697325 | 0.71 | ALDH1A1 (0.68) | LMNAPDE10ACYP3A4TDP1ALDH1A1 | |
| SCHEMBL23719807 | 0.70 | HTT (0.47) | LMNAPDE10ACYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |