SCHEMBL21177750

SCHEMBL21177750

CCCCOC(=O)C(C)[Si](C)(C)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
ATM Q13315 1/20 0.41
TSHR P16473 3/20 0.39
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 2/20 0.38
HCAR2 Q8TDS4 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
NAAA Q02083 1/20 0.36
ALPG P10696 1/20 0.36
PPARG P37231 1/20 0.36
HTT P42858 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21177515 0.95 NAAA (0.43) ALDH1A1TSHRNPSR1HCAR2NAAA
SCHEMBL28442884 0.93 NAAA (0.46) ALDH1A1TSHRNPSR1HCAR2NAAA
SCHEMBL21177762 0.93 NAAA (0.46) ALDH1A1TSHRNPSR1HCAR2NAAA
SCHEMBL21177498 0.93 NAAA (0.46) ALDH1A1TSHRNPSR1HCAR2NAAA
SCHEMBL22614788 0.89 HCAR2 (0.33) ALDH1A1TSHRNPSR1HCAR2TDP1
SCHEMBL22614816 0.84 ALDH1A1 (0.45) ALDH1A1ATMTSHRHPGDNPSR1
SCHEMBL21179456 0.84 ALDH1A1 (0.45) ALDH1A1ATMTSHRHPGDNPSR1
SCHEMBL21177903 0.83 ALDH1A1 (0.39) ALDH1A1TSHRHPGDNPSR1SMN1; SMN2
SCHEMBL22614805 0.81 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDNPSR1
SCHEMBL21180358 0.79 NAAA (0.46) ALDH1A1TSHRNPSR1HCAR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
CN-111601866-B Silicone adhesive composition, cured product, adhesive film, and adhesive tape 信越化学工业株式会社 2022-09-06 CN disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
CN-111601866-A Silicone adhesive composition, adhesive film, and adhesive tape 信越化学工业株式会社 2020-08-28 CN disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed