Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21182288 | 0.78 | NPSR1 (0.43) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12018161 | 0.76 | ALDH1A1 (0.55) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL15609960 | 0.75 | ALDH1A1 (0.54) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL23401834 | 0.74 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL21177630 | 0.74 | MAPK10 (0.41) | MAPTALDH1A1KDM4ETDP1SLC34A1 | |
| SCHEMBL13495154 | 0.74 | SMN1; SMN2 (0.60) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL12003457 | 0.74 | ALDH1A1 (0.53) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9293847 | 0.72 | MAPT (0.45) | NPSR1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12003407 | 0.71 | SMN1; SMN2 (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30681773 | 0.71 | SMN1; SMN2 (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |