Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137115 | 0.87 | TSHR (0.53) | TSHRDTYMKTDP1L3MBTL1GPR35 | |
| SCHEMBL395696 | 0.85 | TSHR (0.56) | TSHRDTYMKTDP1L3MBTL1GPR35 | |
| SCHEMBL26841751 | 0.85 | TSHR (0.56) | TSHRDTYMKTDP1L3MBTL1GPR35 | |
| SCHEMBL14298925 | 0.85 | DTYMK (0.53) | TSHRDTYMKCA1CA2TDP1 | |
| SCHEMBL28196295 | 0.81 | TSHR (0.56) | TSHRDTYMKTDP1L3MBTL1GPR35 | |
| SCHEMBL16676395 | 0.81 | TSHR (0.47) | TSHRDTYMKTDP1L3MBTL1GPR35 | |
| SCHEMBL11991419 | 0.81 | TSHR (0.47) | TSHRDTYMKCA1CA2TDP1 | |
| SCHEMBL4368022 | 0.81 | GPR35 (0.54) | TSHRTDP1GPR35ALDH1A1SNCA | |
| SCHEMBL11697530 | 0.80 | DTYMK (0.60) | TSHRDTYMKCA1CA2TDP1 | |
| SCHEMBL8136865 | 0.79 | TSHR (0.58) | TSHRDTYMKTDP1L3MBTL1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143273-A1 | NOVEL AMIDINE INHIBITORS OF FACTOR XA | ООО "ФармаДиол" | 2019-07-25 | — | — | WO | disclosed |