Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801261 | 0.99 | DHFR (0.48) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL21179129 | 0.99 | DHFR (0.48) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL22801208 | 0.99 | DHFR (0.48) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL21178588 | 0.99 | DHFR (0.48) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL21190271 | 0.93 | DHFR (0.51) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL22801220 | 0.89 | DHFR (0.46) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL22589436 | 0.89 | DHFR (0.61) | DHFRTK2TK1 | |
| SCHEMBL22801181 | 0.89 | DHFR (0.44) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL22801217 | 0.86 | DHFR (0.44) | DHFRLMNASMN1; SMN2MAPTESR1 | |
| SCHEMBL22801202 | 0.85 | DHFR (0.43) | DHFRLMNASMN1; SMN2MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801339-B | 5-Fluorouracil compounds | 纽科利制药公司 | 2025-06-24 | — | — | CN | disclosed |
| US-11427550-B2 | 5-fluorouracil compounds | NUCORION PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2020-12-24 | — | — | US | disclosed |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2020-12-24 | — | — | US | disclosed |
| CN-111801339-A | 5-fluorouracil compounds | 纽科利制药公司 | 2020-10-20 | — | — | CN | disclosed |
| WO-2019143860-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019143860-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | DPYD, DHFR, FAU | DHFR 2/4885LMNA 1225/4885SMN1; SMN2 1144/4885 |
| US-11427550-B2 | 5-fluorouracil compounds | DPYD, DHFR, MTHFD1 | DHFR 2/4885LMNA 1038/4885SMN1; SMN2 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.