Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.41 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3140598 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL1660891 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL30205310 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL232906 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL3143187 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL23004170 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL2787358 | 1.00 | MEN1 (0.48) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL15170574 | 0.98 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Acetic Acid SCHEMBL29142258 | 0.97 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2ABCB11 | |
| Acetic Acid SCHEMBL28358710 | 0.97 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12270152-B2 | Dissolution of cellulose in ionic liquids | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-04-08 | — | — | US | disclosed |
| US-20210079593-A1 | Dissolution of Cellulose in Ionic Liquids | TEXAS TECH UNIVERSITY SYSTEM | 2021-03-18 | — | — | US | disclosed |
| WO-2019143802-A1 | DISSOLUTION OF CELLULOSE IN IONIC LIQUIDS | TEXAS TECH UNIVERSITY SYSTEM (US) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12270152-B2 | Dissolution of cellulose in ionic liquids | CEL, MGAM, SI | ESR1 4813/4885ADRA2A 3672/4885SCN5A 3522/4885 |
| US-20210079593-A1 | Dissolution of Cellulose in Ionic Liquids | CEL, MGAM, SI | ESR1 4813/4885ADRA2A 3672/4885SCN5A 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.