Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121868 | 1.00 | KDM4E (0.40) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL1224772 | 0.85 | KDM4E (0.41) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL31121871 | 0.79 | KDM4E (0.35) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL21177204 | 0.79 | KDM4E (0.35) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL23844379 | 0.75 | KDM4E (0.44) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL10746575 | 0.74 | KDM4E (0.51) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL420824 | 0.74 | KDM4E (0.38) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL424180 | 0.74 | KDM4E (0.38) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL1223405 | 0.72 | LMNA (0.55) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9089149 | 0.71 | HTT (0.42) | KDM4EATMHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740470-B1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-15 | — | — | US | disclosed |
| EP-3740470-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-11-05 | — | — | US | disclosed |
| CN-111615508-A | Amidine substituted benzoyl derivatives useful as herbicides | 先正达参股股份有限公司 | 2020-09-01 | — | — | CN | disclosed |
| WO-2019141740-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | GLRX3, DDT, BROX | KDM4E 548/4885ATM 3889/4885HTT 1421/4885 |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | GLRX3, DDT, BROX | KDM4E 548/4885ATM 3889/4885HTT 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.